$56.00
Disclaimer: This is a research chemical only. It’s not a medication, and it’s not approved for human or animal use outside of authorized studies
| Sequence | Aib‑His‑D‑2‑Nal‑D‑Phe‑Lys‑NH₂ (Ipamorelin) |
| Molecular Formula | C₃₈H₄₉N₉O₅ |
| Molecular Weight | ~711.8 g/mol |
| PubChem CID | 20754357 |
| CAS # | 1170851‑70‑4 |
Ipamorelin is a synthetic pentapeptide classified as a selective growth hormone secretagogue. It exerts its action through specific binding to the ghrelin (GHS-R1a) receptor, stimulating pulsatile secretion of endogenous growth hormone (GH) while exhibiting minimal influence on other pituitary hormones such as cortisol, ACTH, or prolactin.
In experimental settings, Ipamorelin is studied for its role in modulating GH–IGF-1 axis signaling, offering insight into downstream pathways involved in protein synthesis, cellular recovery, metabolic regulation, and musculoskeletal adaptation. Its receptor selectivity makes it a valuable investigative tool for differentiating the isolated effects of GH release from broader endocrine interactions typically triggered by non-specific secretagogues.
Pharmacologically, Ipamorelin demonstrates dose-dependent GH release with relatively low off-target activity, making it a preferred model compound in controlled laboratory studies examining endocrine feedback loops, tissue growth kinetics, and metabolic homeostasis.
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