Retatrutide

Retatrutide is a novel investigational peptide classified as a triple agonist, designed to simultaneously activate three key metabolic hormone receptors: GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors. This trifecta mechanism makes it one of the most advanced and potent compounds under exploration in the field of metabolic and obesity-related research.

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Description

Disclaimer:
Retatrutide is sold strictly for in-vitro laboratory research use only. It is not a drug, food additive, cosmetic, or dietary supplement. This material is not approved by the FDA or any regulatory authority for human or veterinary use, and any discussion of clinical application is for scientific context only—not product endorsement.

Sequence YA1QGTFTSDYSIL2LDKK4AQA1AFIEYLLEGGPSSGAPPPS3
Molecular Formula C₂₂₁H₃₄₂N₄₆O₆₈
Molecular Weight ~4731.3 Da
PubChem CID 485663353
CAS # 2381089‑83‑2

In laboratory settings, Retatrutide is being studied for its effects on appetite regulation, glycemic control, and energy expenditure. Its unique receptor profile aims to mimic and amplify the body’s natural hormonal signals that govern satiety, insulin sensitivity, and fat metabolism. Early-stage clinical data suggest significant reductions in body weight and improvements in glucose homeostasis in models simulating obesity and type 2 diabetes.

Researchers are particularly interested in Retatrutide’s multi-receptor synergy—how simultaneous activation may lead to greater metabolic effects than single or dual agonist peptides. This makes it a critical subject for the study of advanced therapies targeting complex metabolic disorders.

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MG

5 MG, 10 MG, 20 MG, 30 MG

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